
Coenzyme Q10 (CoQ10) is a natural compound that's found in every cell in your body - especially in your heart, kidney, liver and lungs.
Also known as ubiquinone, it's a potent antioxidant that's been nicknamed 'nature’s spark plug’ due to its role in helping your cells convert food into energy.
With various studies showing that CoQ10 may offer a variety of health benefits, the popularity of CoQ10 supplements is on the rise.
But choosing the most effective supplement from the wealth of options available can be difficult.
So we did the research for you... here's our ultimate guide on CoQ-10 - plus the top 5 supplements to consider trying.
What Is CoQ10?
CoQ10, also known as coenzyme Q10, ubiquinol, and ubiquinone, is one of the most powerful antioxidants naturally produced in the human body
It’s responsible for supporting your heart, brain, and muscles, and is also involved in biochemical reactions & the production of cellular energy.
Apart from playing a key role in energy production, CoQ10 is also a potent antioxidant that helps fight harmful free radicals that create oxidative stress in your body. Various trials have demonstrated it may also be beneficial in supporting heart function.
As we age, our bodies naturally produce less Coenzyme Q10. By the age of 80, the amount of CoQ10 in your heart is approximately halved from its peak level.
Low levels of CoQ-10 have been linked to serious long term health issues, so it's important to maintain optimal levels for as long as possible as you get older.
This is why CoQ10 supplements are becoming increasingly popular.
CoQ10 Benefits:

Heart Health

Energy

Fertility

Cells

Skin

Brain Health
Who Can Benefit From CoQ10?

Although everyone needs to maintain optimal CoQ10 levels, there are specific groups who may particularly benefit from CoQ10 supplementation.
CoQ10 levels have been found to be lower in particular groups of people with certain conditions, such as people with heart disease, or people taking cholesterol-lowering drugs like statins which have been shown to hinder your natural production of CoQ10.
People aged 50 years and older, or those who rigorously exercise may also particularly benefit from taking a CoQ10 supplement. Some people also have an inherited genetic deficiency of CoQ10.
CoQ10 Supplements: 2025 Buyers Guide
Coenzyme Q10 supplements come in many different forms, ranging from tablets and capsules, through to drinks, powders, and even gummy vitamins. But not all supplements are created equally.
Here's what to look for and avoid when shopping for a high quality CoQ10 supplement...

3 Things To Look For:
1

Trans Form CoQ10
Trans form CoQ10 is created through a natural yeast fermentation process and is identical to the form of CoQ10 naturally produced by our bodies. Trans form CoQ10 is far superior to cheaper, synthetic versions and so you should ideally look for a supplement containing it wherever possible.

2
Ubiquinone
CoQ10 supplements come in two different forms: Ubiquinone and Ubiquinol. We recommend looking for a supplement made with ubiquinone which is the oxidised form of CoQ10 with proven efficacy. It has been more extensively-studied in terms of clinical trials & typically offers better value for money.

3
Satisfaction Guarantee
Many manufacturers now offer a 100% satisfaction guarantee for as long as 30 or 60 days. This gives you an opportunity to try a supplement "risk free" to ensure you feel the benefits. Plus it shows the company are willing to stand behind the quality and effectiveness of their product.
What To Avoid:
Fillers & Additives
Read the back label of any supplement carefully and watch out for any synthetic fillers or additives. Avoid any unnecessary ingredients or bulking agents such as magnesium stearate, titanium dioxide, starch, iron oxide, or microcrystalline cellulose which don't offer any nutritional benefit.
CoQ10 Tablets
Tablets are not absorbed into the bloodstream as quickly as capsules because they must first be broken down in the stomach. This breakdown process is not always even, which can reduce the effectiveness of the tablet. Tablets also need fillers and binding agents to keep their form and make them easy to consume.
Our #1 CoQ10 Pick For 2025: Puro CoQ10 by Purolabs

For its ultimate combination of triple-strength “trans form” CoQ10 in a pure & potent formula, Puro CoQ10 is going to be the best bet for most people.
Each serving contains a potent dose of naturally fermented CoQ10 and the product is also 100% free from sketchy additives, fillers & bulking agents which are commonly found in most supplements.
But what really sets it apart is the truly comprehensive 60 day, 100% satisfaction guarantee - allowing you to try the product risk-free for 60 days to ensure you see the benefits.
Why You’ll Love Puro CoQ10
Triple strength antioxidant formula with superior quality, research-backed ubiquinone
Made in the UK to the strictest possible manufacturing standards (GMP code of practice)
Tasteless, vegan-friendly capsules (no messy powders or drinks!) in a convenient travel-friendly bottle
Our #1 Pick

Purolabs
Puro CoQ10
From £21.66 per bottle
With an ultra clean formula that's 100% free of any fillers or unnecessary ingredients, this product has over 200+ verified 5-star reviews. Feedback from customers is extremely impressive - with many reporting experiencing improved energy levels, better sleep and improved mood - just to name a few.
Ratings Breakdown
Quality
The commitment to quality is second-to-none. They focus on the highest-quality, most clinically-tested ingredients without the usual additives or fillers commonly found in most supplements.
Quality
The commitment to quality is second-to-none. They focus on the highest-quality, most clinically-tested ingredients without the usual additives & fillers found in most supplements.
Value
You can definitely find CoQ10 supplements cheaper - but if you want true value for money, we think it's worth the investment in your health.
Value
You can definitely find CoQ10 supplements cheaper -- but if you want true value for money, we think it's worth the investment in your health.
Customer Experience
The website is easy to navigate; the delivery is fast and free; and the items come well-packaged. Customer feedback is excellent.
Customer Experience
The website is easy to navigate; the delivery is fast and free; and the items come well-packaged. Customer feedback is excellent.
Brand
While a relative newcomer, the brand has been on the scene for a couple of years now, slowly building their reputation for quality products with premium ingredients.
Brand
While a relative newcomer, the brand has been on the scene for a couple of years now, slowly building their reputation for quality products with premium ingredients
Perks
The product comes with a truly risk-free 60 day 100% satisfaction guarantee so you can try the product first to ensure it's suitable for you.
Perks
The product comes with a truly risk-free 60 day 100% satisfaction guarantee so you can try the product first to ensure it's suitable for you.
Shop Our #1 Pick
Puro CoQ1O by Purolabs
Other Options Worth Considering:

Vegavero Q10 Spray
This innovative spray from German manufacturer Vegovera offers a simple way to boost your CoQ10 intake and includes the bonus of extra added vitamin B1.
The vegan-friendly formula is free from synthetic additives & with a daily dosage of 50mg (5 sprays), each bottle lasts for approximately two months.
With a pleasant pineapple flavour, this is a convenient alternative if you find capsules somewhat difficult to swallow.

Lipolife Lipsomal CoQ10
If liquid supplements are your thing, here's a great offering from Lipolife that provides an impressive 200ml of CoQ10 per 5ml serving.
This product offers a clean & high quality formula sourced from ubiquinone which the manufacturers claim also offers "enhanced nutrient delivery" for superior bioavailability.
Although the taste won't be for everyone & capsules are arguably more convenient, this is a solid option for the money.

Wild & Organic CoQ10 Gummies
Looking to get your daily dose of CoQ10 from a tasty gummy vitamin? Then this product from Wild & Organic is what you've been waiting for.
Each bottle contains 60 chewable tasty banana-flavoured bears - with each 2 gummy serving providing 200mg of CoQ10.
While gummies are always unavoidably a little higher in sugar and additives, we can't think of a tastier way to get your daily dose of goodness.

Qunol Ultra Coq10
This popular softget supplement from Qunol is another excellent option that ticks plenty of boxes.
The manufacturer claims that optimum blood levels of CoQ10 can be reached in just one week due the highly absorbable nature of their patented softgels.
The formula is certainly clean & potent - however it's worth mentioning the softgels are definitely on the larger size if you have some difficulty swallowing.
Shop Our #1 Pick
Puro CoQ10 by Purolabs
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